Molecular Formula | C65H89N17O21S4 |
Molar Mass | 1572.76 |
Density | 1.55±0.1 g/cm3(Predicted) |
Boling Point | 2035.8±65.0 °C(Predicted) |
pKa | 4.02±0.10(Predicted) |
Storage Condition | -20°C,密封,干燥 |
In vitro study | α-Conotoxin AuIB blocks the α3β4 receptor with >100-fold higher potency than other receptor subunit combinations, including α2β2, α2β4, α3β2, α4β2, α4β4, and α1β1γδ. |
biological activity | α-Conotoxin AuIB is a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, Α-conotoxin AuIB blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC50 of 0.75 μm. |
Target | IC50: 0.75 μm (α3β4 nAChR; in Xenopus omeasures) |